Pathogen cross-transmission via building sanitary plumbing systems in a full scale pilot test-rig
Identifieur interne : 000D92 ( Main/Exploration ); précédent : 000D91; suivant : 000D93Pathogen cross-transmission via building sanitary plumbing systems in a full scale pilot test-rig
Auteurs : Michael Gormley ; Thomas J. Aspray ; David A. Kelly ; Cristina Rodriguez-GilSource :
- PLoS ONE [ 1932-6203 ] ; 2017.
Descripteurs français
- KwdFr :
- MESH :
- microbiologie : Eaux d'égout.
- normes : Génie sanitaire.
- pathogénicité : Pseudomonas.
- Génie sanitaire, Humains, Infections bactériennes.
English descriptors
- KwdEn :
- MESH :
- chemical , microbiology : Sewage.
- methods : Sanitary Engineering.
- pathogenicity : Pseudomonas.
- standards : Sanitary Engineering.
- transmission : Bacterial Infections.
- Humans.
Abstract
The WHO Consensus Document on the epidemiology of the SARS epidemic in 2003, included a report on a concentrated outbreak in one Hong Kong housing block which was considered a ‘super-spreading event’. The WHO report conjectured that the sanitary plumbing system was one transmission route for the virus. Empty U-traps allowed the aerosolised virus to enter households from the sewerage system. No biological evidence was presented. This research reports evidence that pathogens can be aerosolised and transported on airstreams within sanitary plumbing systems and enter buildings via empty U-traps. A sanitary plumbing system was built, representing two floors of a building, with simulated toilet flushes on the lower floor and a sterile chamber with extractor fan on the floor above. Cultures of a model organism,
Url:
DOI: 10.1371/journal.pone.0171556
PubMed: 28187135
PubMed Central: 5302810
Affiliations:
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Le document en format XML
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Kelly</name><affiliation><nlm:aff id="aff001"></nlm:aff></affiliation></author><author><name sortKey="Rodriguez Gil, Cristina" sort="Rodriguez Gil, Cristina" uniqKey="Rodriguez Gil C" first="Cristina" last="Rodriguez-Gil">Cristina Rodriguez-Gil</name><affiliation><nlm:aff id="aff001"></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">28187135</idno><idno type="pmc">5302810</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302810</idno><idno type="RBID">PMC:5302810</idno><idno type="doi">10.1371/journal.pone.0171556</idno><date when="2017">2017</date><idno type="wicri:Area/Pmc/Corpus">001352</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001352</idno><idno type="wicri:Area/Pmc/Curation">001352</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001352</idno><idno type="wicri:Area/Pmc/Checkpoint">000600</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000600</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:28187135</idno><idno type="wicri:Area/PubMed/Corpus">000B54</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000B54</idno><idno type="wicri:Area/PubMed/Curation">000B54</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000B54</idno><idno type="wicri:Area/PubMed/Checkpoint">000A86</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000A86</idno><idno type="wicri:Area/Ncbi/Merge">002D66</idno><idno type="wicri:Area/Ncbi/Curation">002D66</idno><idno type="wicri:Area/Ncbi/Checkpoint">002D66</idno><idno type="wicri:Area/Main/Merge">000D94</idno><idno type="wicri:Area/Main/Curation">000D92</idno><idno type="wicri:Area/Main/Exploration">000D92</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Pathogen cross-transmission via building sanitary plumbing systems in a full scale pilot test-rig</title><author><name sortKey="Gormley, Michael" sort="Gormley, Michael" uniqKey="Gormley M" first="Michael" last="Gormley">Michael Gormley</name><affiliation><nlm:aff id="aff001"></nlm:aff></affiliation></author><author><name sortKey="Aspray, Thomas J" sort="Aspray, Thomas J" uniqKey="Aspray T" first="Thomas J." last="Aspray">Thomas J. Aspray</name><affiliation><nlm:aff id="aff001"></nlm:aff></affiliation></author><author><name sortKey="Kelly, David A" sort="Kelly, David A" uniqKey="Kelly D" first="David A." last="Kelly">David A. Kelly</name><affiliation><nlm:aff id="aff001"></nlm:aff></affiliation></author><author><name sortKey="Rodriguez Gil, Cristina" sort="Rodriguez Gil, Cristina" uniqKey="Rodriguez Gil C" first="Cristina" last="Rodriguez-Gil">Cristina Rodriguez-Gil</name><affiliation><nlm:aff id="aff001"></nlm:aff></affiliation></author></analytic><series><title level="j">PLoS ONE</title><idno type="eISSN">1932-6203</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Bacterial Infections (transmission)</term><term>Humans</term><term>Pseudomonas (pathogenicity)</term><term>Sanitary Engineering (methods)</term><term>Sanitary Engineering (standards)</term><term>Sewage (microbiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Eaux d'égout (microbiologie)</term><term>Génie sanitaire ()</term><term>Génie sanitaire (normes)</term><term>Humains</term><term>Infections bactériennes (transmission)</term><term>Pseudomonas (pathogénicité)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="microbiology" xml:lang="en"><term>Sewage</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Sanitary Engineering</term></keywords><keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Eaux d'égout</term></keywords><keywords scheme="MESH" qualifier="normes" xml:lang="fr"><term>Génie sanitaire</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Pseudomonas</term></keywords><keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Pseudomonas</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Sanitary Engineering</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Bacterial Infections</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Génie sanitaire</term><term>Humains</term><term>Infections bactériennes</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The WHO Consensus Document on the epidemiology of the SARS epidemic in 2003, included a report on a concentrated outbreak in one Hong Kong housing block which was considered a ‘super-spreading event’. The WHO report conjectured that the sanitary plumbing system was one transmission route for the virus. Empty U-traps allowed the aerosolised virus to enter households from the sewerage system. No biological evidence was presented. This research reports evidence that pathogens can be aerosolised and transported on airstreams within sanitary plumbing systems and enter buildings via empty U-traps. A sanitary plumbing system was built, representing two floors of a building, with simulated toilet flushes on the lower floor and a sterile chamber with extractor fan on the floor above. Cultures of a model organism, <italic>Pseudomonas putida</italic> at 10<sup>6</sup>–10<sup>9</sup> cfu ml<sup>-1</sup> in 0·85% NaCl were flushed into the system in volumes of 6 to 20 litres to represent single or multiple toilet flushes. Air and surface samples were cultured on agar plates and assessed qualitatively and semi-quantitatively. Flushing from a toilet into a sanitary plumbing system generated enough turbulence to aerosolise pathogens. Typical sanitary plumbing system airflows (between 20–30 ls<sup>-1</sup>) were sufficient to carry aerosolised pathogens between different floors of a building. Empty U-traps allowed aerosolised pathogens to enter the chamber, encouraging cross-transmission. All parts of the system were found to be contaminated post-flush. Empty U-traps have been observed in many buildings and a risk assessment indicates the potential for high risk cross-transmission under defect conditions in buildings with high pathogen loading such as hospitals. Under defective conditions (which are not uncommon) aerosolised pathogens can be carried on the airflows within sanitary plumbing systems. Our findings show that greater consideration should be given to this mode of pathogen transmission.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Moore, G" uniqKey="Moore G">G Moore</name></author><author><name sortKey="Walker, Jt" uniqKey="Walker J">JT Walker</name></author><author><name sortKey="Percival, Sl" uniqKey="Percival S">SL Percival</name></author><author><name sortKey="Randle, J" uniqKey="Randle J">J Randle</name></author><author><name sortKey="Cooper, T" uniqKey="Cooper T">T Cooper</name></author><author><name sortKey="Williams, D" uniqKey="Williams D">D Williams</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Moore, G" uniqKey="Moore G">G Moore</name></author><author><name sortKey="Stevenson, D" uniqKey="Stevenson D">D Stevenson</name></author><author><name sortKey="Thompson, K A" uniqKey="Thompson K">K-A Thompson</name></author><author><name sortKey="Parks, S" uniqKey="Parks S">S Parks</name></author><author><name sortKey="Ngabo, D" uniqKey="Ngabo D">D Ngabo</name></author><author><name sortKey="Bennett, Am" uniqKey="Bennett A">AM Bennett</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Walker, Jt" uniqKey="Walker J">JT Walker</name></author><author><name sortKey="Moore, G" uniqKey="Moore G">G. 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Gormley</name></author></analytic></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="Aspray, Thomas J" sort="Aspray, Thomas J" uniqKey="Aspray T" first="Thomas J." last="Aspray">Thomas J. Aspray</name><name sortKey="Gormley, Michael" sort="Gormley, Michael" uniqKey="Gormley M" first="Michael" last="Gormley">Michael Gormley</name><name sortKey="Kelly, David A" sort="Kelly, David A" uniqKey="Kelly D" first="David A." last="Kelly">David A. Kelly</name><name sortKey="Rodriguez Gil, Cristina" sort="Rodriguez Gil, Cristina" uniqKey="Rodriguez Gil C" first="Cristina" last="Rodriguez-Gil">Cristina Rodriguez-Gil</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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